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The Dlt and LiaFSR systems derepress SpeB production independently in the Δpde2 mutant of Streptococcus pyogenes

The second messenger molecule, c-di-AMP, plays a critical role in pathogenesis and virulence in S. pyogenes. We previously reported that deleting the c-di-AMP phosphodiesterase gene pde2 severely suppresses SpeB production at the transcriptional level. We performed transposon mutagenesis to gain ins...

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Detalles Bibliográficos
Autores principales: Faozia, Sabrina, Hossain, Tasmim, Cho, Kyu Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679467/
https://www.ncbi.nlm.nih.gov/pubmed/38029265
http://dx.doi.org/10.3389/fcimb.2023.1293095