The N-terminus of Stag1 is required to repress the 2C program by maintaining rRNA expression and nucleolar integrity

Our understanding of how STAG proteins contribute to cell identity and disease have largely been studied from the perspective of chromosome topology and protein-coding gene expression. Here, we show that STAG1 is the dominant paralog in mouse embryonic stem cells (mESCs) and is required for pluripot...

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Detalles Bibliográficos
Autores principales: Pezic, Dubravka, Weeks, Samuel, Varsally, Wazeer, Dewari, Pooran S., Pollard, Steven, Branco, Miguel R., Hadjur, Suzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679541/
https://www.ncbi.nlm.nih.gov/pubmed/37802073
http://dx.doi.org/10.1016/j.stemcr.2023.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679541/
https://www.ncbi.nlm.nih.gov/pubmed/37802073
http://dx.doi.org/10.1016/j.stemcr.2023.09.004

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