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The N-terminus of Stag1 is required to repress the 2C program by maintaining rRNA expression and nucleolar integrity
Our understanding of how STAG proteins contribute to cell identity and disease have largely been studied from the perspective of chromosome topology and protein-coding gene expression. Here, we show that STAG1 is the dominant paralog in mouse embryonic stem cells (mESCs) and is required for pluripot...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679541/ https://www.ncbi.nlm.nih.gov/pubmed/37802073 http://dx.doi.org/10.1016/j.stemcr.2023.09.004 |