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A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM
Retinoic acid (RA) induces an atrial phenotype in human induced pluripotent stem cells (hiPSCs), but expression of atrium-selective currents such as the ultrarapid (I(Kur)) and acetylcholine-stimulated K(+) current is variable and less than in the adult human atrium. We suspected methodological issu...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679650/ https://www.ncbi.nlm.nih.gov/pubmed/37922915 http://dx.doi.org/10.1016/j.stemcr.2023.10.006 |