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The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5
Congenital heart disease often arises from perturbations of transcription factors (TFs) that guide cardiac development. ISLET1 (ISL1) is a TF that influences early cardiac cell fate, as well as differentiation of other cell types including motor neuron progenitors (MNPs) and pancreatic islet cells....
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679653/ https://www.ncbi.nlm.nih.gov/pubmed/37863045 http://dx.doi.org/10.1016/j.stemcr.2023.09.014 |