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The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5

Congenital heart disease often arises from perturbations of transcription factors (TFs) that guide cardiac development. ISLET1 (ISL1) is a TF that influences early cardiac cell fate, as well as differentiation of other cell types including motor neuron progenitors (MNPs) and pancreatic islet cells....

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Detalles Bibliográficos
Autores principales: Maven, Bonnie E.J., Gifford, Casey A., Weilert, Melanie, Gonzalez-Teran, Barbara, Hüttenhain, Ruth, Pelonero, Angelo, Ivey, Kathryn N., Samse-Knapp, Kaitlen, Kwong, Wesley, Gordon, David, McGregor, Michael, Nishino, Tomohiro, Okorie, Eyuche, Rossman, Sage, Costa, Mauro W., Krogan, Nevan J., Zeitlinger, Julia, Srivastava, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679653/
https://www.ncbi.nlm.nih.gov/pubmed/37863045
http://dx.doi.org/10.1016/j.stemcr.2023.09.014