AT7867 promotes pancreatic progenitor differentiation of human iPSCs

Generation of pure pancreatic progenitor (PP) cells is critical for clinical translation of stem cell-derived islets. Herein, we performed PP differentiation with and without AKT/P70 inhibitor AT7867 and characterized the resulting cells at protein and transcript level in vitro and in vivo upon tran...

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Detalles Bibliográficos
Autores principales: Cuesta-Gomez, Nerea, Verhoeff, Kevin, Dadheech, Nidheesh, Pawlick, Rena, Marfil-Garza, Braulio, Razavy, Haide, Shapiro, A.M. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679659/
https://www.ncbi.nlm.nih.gov/pubmed/37922913
http://dx.doi.org/10.1016/j.stemcr.2023.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679659/
https://www.ncbi.nlm.nih.gov/pubmed/37922913
http://dx.doi.org/10.1016/j.stemcr.2023.10.005

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