Cargando…

AT7867 promotes pancreatic progenitor differentiation of human iPSCs

Generation of pure pancreatic progenitor (PP) cells is critical for clinical translation of stem cell-derived islets. Herein, we performed PP differentiation with and without AKT/P70 inhibitor AT7867 and characterized the resulting cells at protein and transcript level in vitro and in vivo upon tran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cuesta-Gomez, Nerea, Verhoeff, Kevin, Dadheech, Nidheesh, Pawlick, Rena, Marfil-Garza, Braulio, Razavy, Haide, Shapiro, A.M. James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679659/ https://www.ncbi.nlm.nih.gov/pubmed/37922913 http://dx.doi.org/10.1016/j.stemcr.2023.10.005

Ejemplares similares

Suspension culture improves iPSC expansion and pluripotency phenotype
por: Cuesta-Gomez, Nerea, et al.
Publicado: (2023)

The Current Status of Allogenic Islet Cell Transplantation
por: Czarnecka, Zofia, et al.
Publicado: (2023)

Mitochondrial regulation in human pluripotent stem cells during reprogramming and β cell differentiation
por: Jasra, Ila Tewari, et al.
Publicado: (2023)

Pan-caspase inhibitor F573 mitigates liver ischemia reperfusion injury in a murine model
por: Bral, Mariusz, et al.
Publicado: (2019)

Inducible Pluripotent Stem Cells as a Potential Cure for Diabetes
por: Verhoeff, Kevin, et al.
Publicado: (2021)

Lucky iPSCs
por: Zviran, Asaf, et al.
Publicado: (2014)

iPSCs are safe!
por: Yan, Hualong, et al.
Publicado: (2017)

Therapeutic Effect of a Novel Oxazolidinone, DA-7867, in BALB/c Mice Infected with Nocardia brasiliensis
por: Vera-Cabrera, Lucio, et al.
Publicado: (2008)

Preclinical models of acute liver failure: a comprehensive review
por: Hefler, Joshua, et al.
Publicado: (2021)

Human neural progenitors derived from integration-free iPSCs for SCI therapy
por: Liu, Ying, et al.
Publicado: (2017)

Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs
por: Llorente, Irene L., et al.
Publicado: (2021)

Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages
por: Lipus, Alexandra, et al.
Publicado: (2020)

Mitochondria fingerprint longevity in iPSCs
por: Masotti, Andrea, et al.
Publicado: (2015)

Applications of iPSCs in Cancer Research
por: Kim, Jean J
Publicado: (2015)

Reducing genomic instability in iPSCs
por: Ruiz, Sergio, et al.
Publicado: (2015)

The Challenge of Bringing iPSCs to the Patient
por: Ortuño-Costela, María del Carmen, et al.
Publicado: (2019)

iPSCs in Modeling and Therapy of Osteoarthritis
por: Csobonyeiova, Maria, et al.
Publicado: (2021)

Generation, expansion, and drug treatment of hematopoietic progenitor cells derived from human iPSCs
por: Dannenmann, Benjamin, et al.
Publicado: (2022)

Differentiation of Human Induced Pluripotent Stem Cells (iPSCs)–derived Mesenchymal Progenitors into Chondrocytes
por: Khan, Nazir M., et al.
Publicado: (2023)

iPSCs: From Bench to Clinical Bed
por: Li, Yujing, et al.
Publicado: (2016)

Differentiation of human iPSCs into functional podocytes
por: Rauch, Caroline, et al.
Publicado: (2018)

Extracellular matrix-derived peptide stimulates the generation of endocrine progenitors and islet organoids from iPSCs
por: Heaton, Emma S, et al.
Publicado: (2023)

AT7867 Inhibits Human Colorectal Cancer Cells via AKT-Dependent and AKT-Independent Mechanisms
por: Zhang, Shihu, et al.
Publicado: (2017)

Nanog-Independent Reprogramming to iPSCs with Canonical Factors
por: Carter, Ava C., et al.
Publicado: (2014)

Disease, iPSCs and a Quest for the Perfect Model
Publicado: (2016)

Clinical Therapy Using iPSCs: Hopes and Challenges
por: Lu, Xiao, et al.
Publicado: (2013)

The Potential of iPSCs for the Treatment of Premature Aging Disorders
por: Compagnucci, Claudia, et al.
Publicado: (2017)

The tale of autologous iPSCs: A monkey perspective
por: Li, Fei
Publicado: (2014)

Tumorigenicity risk of iPSCs in vivo: nip it in the bud
por: Zhong, Chaoliang, et al.
Publicado: (2022)

Functional genomics and the future of iPSCs in disease modeling
por: Brooks, Imogen R., et al.
Publicado: (2022)

Modelling urea cycle disorders using iPSCs
por: Duff, Claire, et al.
Publicado: (2022)

iPSCs in NK Cell Manufacturing and NKEV Development
por: Boyd-Gibbins, Nicholas, et al.
Publicado: (2022)

MSCs vs. iPSCs: Potential in therapeutic applications
por: Thanaskody, Kalaiselvaan, et al.
Publicado: (2022)

Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons
por: Magliocca, Valentina, et al.
Publicado: (2017)

Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes
por: Arnst, Nikita, et al.
Publicado: (2021)

Swertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo Study
por: Dadheech, Nidheesh, et al.
Publicado: (2015)

Modelling DMD-associated cardiomyopathy in patient-derived iPSCs
Publicado: (2015)

The State of Play with iPSCs and Spinal Cord Injury Models
por: Hodgetts, Stuart I., et al.
Publicado: (2015)

An Overview of Direct Somatic Reprogramming: The Ins and Outs of iPSCs
por: Menon, Siddharth, et al.
Publicado: (2016)

Epigenetic Modifiers Facilitate Induction and Pluripotency of Porcine iPSCs
por: Mao, Jian, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jqpoq1qpfrhlj8kl38ile34795