Cargando…
Mowat-Wilson syndrome factor ZEB2 controls early formation of human neural crest through BMP signaling modulation
Mowat-Wilson syndrome is caused by mutations in ZEB2, with patients exhibiting characteristics indicative of neural crest (NC) defects. We examined the contribution of ZEB2 to human NC formation using a model based on human embryonic stem cells. We found ZEB2 to be one of the earliest factors expres...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679662/ https://www.ncbi.nlm.nih.gov/pubmed/37890485 http://dx.doi.org/10.1016/j.stemcr.2023.10.002 |