Mowat-Wilson syndrome factor ZEB2 controls early formation of human neural crest through BMP signaling modulation

Mowat-Wilson syndrome is caused by mutations in ZEB2, with patients exhibiting characteristics indicative of neural crest (NC) defects. We examined the contribution of ZEB2 to human NC formation using a model based on human embryonic stem cells. We found ZEB2 to be one of the earliest factors expres...

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Detalles Bibliográficos
Autores principales: Charney, Rebekah M., Prasad, Maneeshi S., Juan-Sing, Czarina, Patel, Lipsa J., Hernandez, Jacqueline C., Wu, Jie, García-Castro, Martín I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679662/
https://www.ncbi.nlm.nih.gov/pubmed/37890485
http://dx.doi.org/10.1016/j.stemcr.2023.10.002

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