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PITX2 gain-of-function mutation associated with atrial fibrillation alters mitochondrial activity in human iPSC atrial-like cardiomyocytes

Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide; however, the underlying causes of AF initiation are still poorly understood, particularly because currently available models do not allow in distinguishing the initial causes from maladaptive remodeling that induces and perpet...

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Detalles Bibliográficos
Autores principales: Benzoni, Patrizia, Da Dalt, Lorenzo, Elia, Noemi, Popolizio, Vera, Cospito, Alessandro, Giannetti, Federica, Dell’Era, Patrizia, Olesen, Morten S., Bucchi, Annalisa, Baruscotti, Mirko, Norata, Giuseppe Danilo, Barbuti, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679737/
https://www.ncbi.nlm.nih.gov/pubmed/38028792
http://dx.doi.org/10.3389/fphys.2023.1250951