Injectable hydrogel with selenium nanoparticles delivery for sustained glutathione peroxidase activation and enhanced osteoarthritis therapeutics

Reactive oxygen burst in articular chondrocytes is a major contributor to osteoarthritis progression. Although selenium is indispensable role in the antioxidant process, the narrow therapeutic window, delicate toxicity margins, and lack of an efficient delivery system have hindered its translation t...

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Detalles Bibliográficos
Autores principales: Hu, Wenhui, Yao, Xuan, Li, Yuheng, Li, Jianmei, Zhang, Jing, Zou, Zhi, Kang, Fei, Dong, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679772/
https://www.ncbi.nlm.nih.gov/pubmed/38024839
http://dx.doi.org/10.1016/j.mtbio.2023.100864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679772/
https://www.ncbi.nlm.nih.gov/pubmed/38024839
http://dx.doi.org/10.1016/j.mtbio.2023.100864

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