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Super-enhancer driven SOX2 promotes tumor formation by chromatin re-organization in nasopharyngeal carcinoma

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a malignant head and neck cancer with a high incidence in Southern China and Southeast Asia. Patients with remote metastasis and recurrent NPC have poor prognosis. Thus, a better understanding of NPC pathogenesis may identify novel therapies to address t...

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Detalles Bibliográficos
Autores principales: Liu, Shang-Xin, Wang, Chong, Lin, Ruo-Bin, Ding, Wei-Yue, Roy, Gaurab, Wang, Hong-Bo, Yang, Ting, Liu, Qian, Luo, Yi-Ling, Jin, Shui-Lin, Zeng, Mu-Sheng, Zhao, Bo, Zhong, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679863/
https://www.ncbi.nlm.nih.gov/pubmed/37967508
http://dx.doi.org/10.1016/j.ebiom.2023.104870