PHD3 inhibits colon cancer cell metastasis through the occludin-p38 pathway: PHD3 inhibits metastasis via occludin-p38 MAPK

Prolyl hydroxylase 3 (PHD3) hydroxylates HIFα in the presence of oxygen, leading to HIFα degradation. PHD3 inhibits tumorigenesis. However, the underlying mechanism is not well understood. Herein, we demonstrate that PHD3 inhibits the metastasis of colon cancer cells through the occludin-p38 MAPK pa...

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Detalles Bibliográficos
Autores principales: Li, Yuyao, Yuan, Tanglong, Zhang, Hongwei, Liu, Shuting, Lun, Jie, Guo, Jing, Wang, Yu, Zhang, Yuying, Fang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679873/
https://www.ncbi.nlm.nih.gov/pubmed/37814811
http://dx.doi.org/10.3724/abbs.2023103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679873/
https://www.ncbi.nlm.nih.gov/pubmed/37814811
http://dx.doi.org/10.3724/abbs.2023103

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