TLR7 neo-functionalizes to sense dsRNA and trigger antiviral and antibacterial immunity in non-tetrapod vertebrates

TLR7 plays a crucial role in sensing viral ssRNA and initiating immune responses. Piscine TLR7 also responds to dsRNA challenge. dsRNA exists in almost all the viruses at specific stages. However, the mechanism on sensing dsRNA by TLR7 remains unknown. In the present study, we employed Ctenopharyngo...

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Detalles Bibliográficos
Autores principales: Jiang, Rui, Zhu, Wentao, Liao, Zhiwei, Yang, Chunrong, Su, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679900/
https://www.ncbi.nlm.nih.gov/pubmed/38025781
http://dx.doi.org/10.1016/j.isci.2023.108315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679900/
https://www.ncbi.nlm.nih.gov/pubmed/38025781
http://dx.doi.org/10.1016/j.isci.2023.108315

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