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Stem cell factor inhibition reduces Th2 inflammation and cellular infiltration in a mouse model of eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a T helper (Th)2-mediated inflammatory disorder characterized endoscopically by eosinophilic infiltration leading to fibrosis of the esophagus. Stem cell factor (SCF), a multifunctional cytokine, is upregulated in several allergic diseases, including in patients wit...

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Detalles Bibliográficos
Autores principales: Ptaschinski, Catherine, Zhu, Diana, Fonseca, Wendy, Lukacs, Nicholas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680063/
https://www.ncbi.nlm.nih.gov/pubmed/37557983
http://dx.doi.org/10.1016/j.mucimm.2023.07.006