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Stem cell factor inhibition reduces Th2 inflammation and cellular infiltration in a mouse model of eosinophilic esophagitis
Eosinophilic esophagitis (EoE) is a T helper (Th)2-mediated inflammatory disorder characterized endoscopically by eosinophilic infiltration leading to fibrosis of the esophagus. Stem cell factor (SCF), a multifunctional cytokine, is upregulated in several allergic diseases, including in patients wit...
Autores principales: | Ptaschinski, Catherine, Zhu, Diana, Fonseca, Wendy, Lukacs, Nicholas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680063/ https://www.ncbi.nlm.nih.gov/pubmed/37557983 http://dx.doi.org/10.1016/j.mucimm.2023.07.006 |
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