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The intrinsically disordered region of eIF5B stimulates IRES usage and nucleates biological granule formation
Cells activate stress response pathways to survive adverse conditions. Such responses involve the inhibition of global cap-dependent translation. This inhibition is a block that essential transcripts must escape via alternative methods of translation initiation, e.g., an internal ribosome entry site...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680144/ https://www.ncbi.nlm.nih.gov/pubmed/37862172 http://dx.doi.org/10.1016/j.celrep.2023.113283 |