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The intrinsically disordered region of eIF5B stimulates IRES usage and nucleates biological granule formation

Cells activate stress response pathways to survive adverse conditions. Such responses involve the inhibition of global cap-dependent translation. This inhibition is a block that essential transcripts must escape via alternative methods of translation initiation, e.g., an internal ribosome entry site...

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Detalles Bibliográficos
Autores principales: Harris, Meghan T., Marr, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680144/
https://www.ncbi.nlm.nih.gov/pubmed/37862172
http://dx.doi.org/10.1016/j.celrep.2023.113283