Anti-TIM3 chimeric antigen receptor-natural killer cells from engineered induced pluripotent stem cells effectively target acute myeloid leukemia cells

BACKGROUND: Acute myeloid leukemia (AML) is a clonal malignant disorder which originates from a small number of leukemia-initiating cells or leukemic stem cells (LSCs)—the subpopulation that is also the root cause of relapsed/refractory AML. Chimeric antigen receptor (CAR)-T cell therapy has proved...

Descripción completa

Detalles Bibliográficos
Autores principales: Klaihmon, Phatchanat, Luanpitpong, Sudjit, Kang, Xing, Issaragrisil, Surapol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680184/
https://www.ncbi.nlm.nih.gov/pubmed/38012684
http://dx.doi.org/10.1186/s12935-023-03153-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680184/
https://www.ncbi.nlm.nih.gov/pubmed/38012684
http://dx.doi.org/10.1186/s12935-023-03153-9

Ejemplares similares