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Inhibition of microfold cells ameliorates early pathological phenotypes by modulating microglial functions in Alzheimer’s disease mouse model

BACKGROUND: The gut microbiota has recently attracted attention as a pathogenic factor in Alzheimer’s disease (AD). Microfold (M) cells, which play a crucial role in the gut immune response against external antigens, are also exploited for the entry of pathogenic bacteria and proteins into the body....

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Detalles Bibliográficos
Autores principales: Kim, Namkwon, Ju, In Gyoung, Jeon, Seung Ho, Lee, Yeongae, Jung, Min-Ji, Gee, Min Sung, Cho, Jae Seok, Inn, Kyung-Soo, Garrett-Sinha, Lee Ann, Oh, Myung Sook, Lee, Jong Kil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680211/
https://www.ncbi.nlm.nih.gov/pubmed/38012646
http://dx.doi.org/10.1186/s12974-023-02966-9