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Inhibition of microfold cells ameliorates early pathological phenotypes by modulating microglial functions in Alzheimer’s disease mouse model
BACKGROUND: The gut microbiota has recently attracted attention as a pathogenic factor in Alzheimer’s disease (AD). Microfold (M) cells, which play a crucial role in the gut immune response against external antigens, are also exploited for the entry of pathogenic bacteria and proteins into the body....
Autores principales: | Kim, Namkwon, Ju, In Gyoung, Jeon, Seung Ho, Lee, Yeongae, Jung, Min-Ji, Gee, Min Sung, Cho, Jae Seok, Inn, Kyung-Soo, Garrett-Sinha, Lee Ann, Oh, Myung Sook, Lee, Jong Kil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680211/ https://www.ncbi.nlm.nih.gov/pubmed/38012646 http://dx.doi.org/10.1186/s12974-023-02966-9 |
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