The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13–MAPK–YWHAE signaling pathway

BACKGROUND: Multiple myeloma (MM), an incurable disease owing to drug resistance, requires safe and effective therapies. Norcantharidin (NCTD), an active ingredient in traditional Chinese medicines, possesses activity against different cancers. However, its toxicity and narrow treatment window limit...

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Detalles Bibliográficos
Autores principales: Wang, Yingcong, Dong, Sanfeng, Hu, Ke, Xu, Li, Feng, Qilin, Li, Bo, Wang, Guangli, Chen, Gege, Zhang, Bibo, Jia, Xinyan, Xu, Zhijian, Gao, Xuejie, Zhang, Hui, Xie, Yongsheng, Lu, Meiling, Chang, Shuaikang, Song, Dongliang, Wu, Xiaosong, Jia, Qi, Zhu, Huabin, Zhou, Jinfeng, Zhu, Weiliang, Shi, Jumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680230/
https://www.ncbi.nlm.nih.gov/pubmed/38012658
http://dx.doi.org/10.1186/s12967-023-04739-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680230/
https://www.ncbi.nlm.nih.gov/pubmed/38012658
http://dx.doi.org/10.1186/s12967-023-04739-7

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