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TET2 deficiency promotes anxiety and depression-like behaviors by activating NLRP3/IL-1β pathway in microglia of allergic rhinitis mice

BACKGROUND: Anxiety and depression-like behaviors in allergic rhinitis (AR) are attracting attention, while the precise mechanism has not been clearly elucidated. Recent evidence shows that neuroinflammation in anterior cingulate cortex (ACC) may be the core of these neuropsychiatric symptoms in AR....

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Detalles Bibliográficos
Autores principales: Gao, Ziang, Lv, Hao, Wang, Yunfei, Xie, Yulie, Guan, Mengting, Xu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680276/
https://www.ncbi.nlm.nih.gov/pubmed/38012545
http://dx.doi.org/10.1186/s10020-023-00757-9