GITR and TIGIT immunotherapy provokes divergent multicellular responses in the tumor microenvironment of gastrointestinal cancers

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BACKGROUND: Understanding the mechanistic effects of novel immunotherapy agents is critical to improving their successful clinical translation. These effects need to be studied in preclinical models that maintain the heterogenous tumor microenvironment (TME) and dysfunctional cell states found in a...

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Detalles Bibliográficos
Autores principales: Sathe, Anuja, Ayala, Carlos, Bai, Xiangqi, Grimes, Susan M., Lee, Byrne, Kin, Cindy, Shelton, Andrew, Poultsides, George, Ji, Hanlee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680277/
https://www.ncbi.nlm.nih.gov/pubmed/38008725
http://dx.doi.org/10.1186/s13073-023-01259-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680277/
https://www.ncbi.nlm.nih.gov/pubmed/38008725
http://dx.doi.org/10.1186/s13073-023-01259-3

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