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Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer

BACKGROUND: Enhancer dysregulation is one of the important features for cancer cells. Enhancers enriched with H3K4me3 have been implicated to play important roles in cancer. However, their detailed features and regulatory mechanisms have not been well characterized. RESULTS: Here, we profile the lan...

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Detalles Bibliográficos
Autores principales: Lin, Xiang, Chen, Ji-Dong, Wang, Chen-Yu, Cai, Zhen, Zhan, Rui, Yang, Chen, Zhang, La-Ying, Li, Lian-Yun, Xiao, Yong, Chen, Ming-Kai, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680327/
https://www.ncbi.nlm.nih.gov/pubmed/38012744
http://dx.doi.org/10.1186/s13059-023-03108-3