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AptaTrans: a deep neural network for predicting aptamer-protein interaction using pretrained encoders
BACKGROUND: Aptamers, which are biomaterials comprised of single-stranded DNA/RNA that form tertiary structures, have significant potential as next-generation materials, particularly for drug discovery. The systematic evolution of ligands by exponential enrichment (SELEX) method is a critical in vit...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680337/ https://www.ncbi.nlm.nih.gov/pubmed/38012571 http://dx.doi.org/10.1186/s12859-023-05577-6 |