AptaTrans: a deep neural network for predicting aptamer-protein interaction using pretrained encoders

BACKGROUND: Aptamers, which are biomaterials comprised of single-stranded DNA/RNA that form tertiary structures, have significant potential as next-generation materials, particularly for drug discovery. The systematic evolution of ligands by exponential enrichment (SELEX) method is a critical in vit...

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Detalles Bibliográficos
Autores principales: Shin, Incheol, Kang, Keumseok, Kim, Juseong, Sel, Sanghun, Choi, Jeonghoon, Lee, Jae-Wook, Kang, Ho Young, Song, Giltae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680337/
https://www.ncbi.nlm.nih.gov/pubmed/38012571
http://dx.doi.org/10.1186/s12859-023-05577-6

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