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Pericyte-derived exosomal miR-210 improves mitochondrial function and inhibits lipid peroxidation in vascular endothelial cells after traumatic spinal cord injury by activating JAK1/STAT3 signaling pathway

BACKGROUND: Spinal cord injury (SCI) remains a significant health concern, with limited available treatment options. This condition poses significant medical, economic, and social challenges. SCI is typically categorized into primary and secondary injuries. Inflammation, oxidative stress, scar forma...

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Detalles Bibliográficos
Autores principales: Gao, Peng, Yi, Jiang, Chen, Wenjun, Gu, Jun, Miao, Sheng, Wang, Xiaowei, Huang, Yifan, Jiang, Tao, Li, Qingqing, Zhou, Wei, Zhao, Shujie, Wu, Mengyuan, Yin, Guoyong, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680350/
https://www.ncbi.nlm.nih.gov/pubmed/38012616
http://dx.doi.org/10.1186/s12951-023-02110-y