Differential metabolic alterations in IDH1 mutant vs. wildtype glioma cells promote epileptogenesis through distinctive mechanisms

Glioma-related epilepsy (GRE) is a hallmark clinical presentation of gliomas with significant impacts on patient quality of life. The current standard of care for seizure management is comprised of anti-seizure medications (ASMs) and surgical resection. Seizures in glioma patients are often drug-res...

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Detalles Bibliográficos
Autores principales: McAfee, Darrian, Moyer, Mitchell, Queen, Jaden, Mortazavi, Armin, Boddeti, Ujwal, Bachani, Muzna, Zaghloul, Kareem, Ksendzovsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680369/
https://www.ncbi.nlm.nih.gov/pubmed/38026690
http://dx.doi.org/10.3389/fncel.2023.1288918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680369/
https://www.ncbi.nlm.nih.gov/pubmed/38026690
http://dx.doi.org/10.3389/fncel.2023.1288918

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