Influence of metabolic stress and metformin on synaptic protein profile in SH‐SY5Y‐derived neurons

Insulin resistance (IR) is associated with reductions in neuronal proteins often observed with Alzheimer's disease (AD), however, the mechanisms through which IR promotes neurodegeneration/AD pathogenesis are poorly understood. Metformin (MET), a potent activator of the metabolic regulator AMPK...

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Detalles Bibliográficos
Autores principales: Yang, Alex J. T., Mohammad, Ahmad, Finch, Michael S., Tsiani, Evangelia, Spencer, Gaynor, Necakov, Aleksandar, MacPherson, Rebecca E. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680579/
https://www.ncbi.nlm.nih.gov/pubmed/38010200
http://dx.doi.org/10.14814/phy2.15852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680579/
https://www.ncbi.nlm.nih.gov/pubmed/38010200
http://dx.doi.org/10.14814/phy2.15852

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