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The anti-B7-H3 blocking antibody MJ18 does not recognize B7-H3 in murine tumor models

The immune checkpoint molecule B7-H3 is regarded as one of the most promising therapeutic targets for the treatment of human cancers. B7-H3 is highly expressed in many cancers and its expression has been associated to impaired antitumor immunity and poor patient prognosis. In immunocompetent mouse t...

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Detalles Bibliográficos
Autores principales: Nammor, Talah, Frizzell, Jenna, Lavoie, Roxane R., Lucien, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680724/
https://www.ncbi.nlm.nih.gov/pubmed/38014341
http://dx.doi.org/10.1101/2023.11.15.567261