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A chemical structure and machine learning approach to assess the potential bioactivity of endogenous metabolites and their association with early-childhood hs-CRP levels

Metabolomics has gained much attraction due to its potential to reveal molecular disease mechanisms and present viable biomarkers. In this work we used a panel of untargeted serum metabolomes in 602 childhood patients of the COPSAC2010 mother-child cohort. The annotated part of the metabolome consis...

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Detalles Bibliográficos
Autores principales: Lovrić, Mario, Wang, Tingting, Staffe, Mads Rønnow, Šunić, Iva, Časni, Kristina, Lasky-Su, Jessica, Chawes, Bo, Rasmussen, Morten Arendt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680762/
https://www.ncbi.nlm.nih.gov/pubmed/38014335
http://dx.doi.org/10.1101/2023.11.15.567095