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Fungi of the order Mucorales express a “sealing-only” tRNA ligase

Some eukaryotic pre-tRNAs contain an intron that is removed by a dedicated set of enzymes. Intron-containing pre-tRNAs are cleaved by tRNA splicing endonuclease (TSEN), followed by ligation of the two exons and release of the intron. Fungi use a “heal and seal” pathway that requires three distinct c...

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Detalles Bibliográficos
Autores principales: Ahammed, Khondakar Sayef, van Hoof, Ambro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680797/
https://www.ncbi.nlm.nih.gov/pubmed/38014270
http://dx.doi.org/10.1101/2023.11.16.567474