High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia

Due to their immunomodulatory function, mesenchymal stromal cells (MSCs) are a promising therapeutic with the potential to treat neuroinflammation associated with neurodegenerative diseases. This function can be mediated by secreted extracellular vesicles (MSC-EVs). Despite established safety, MSC c...

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Detalles Bibliográficos
Autores principales: Larey, Andrew M., Spoerer, Thomas M., Daga, Kanupriya R., Morfin, Maria G., Hynds, Hannah M., Carpenter, Jana, Hines, Kelly M., Marklein, Ross A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680807/
https://www.ncbi.nlm.nih.gov/pubmed/38014258
http://dx.doi.org/10.1101/2023.11.19.567730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680807/
https://www.ncbi.nlm.nih.gov/pubmed/38014258
http://dx.doi.org/10.1101/2023.11.19.567730

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