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JUN mRNA Translation Regulation is Mediated by Multiple 5’ UTR and Start Codon Features

Regulation of mRNA translation by eukaryotic initiation factors (eIFs) is crucial for cell survival. In humans, eIF3 stimulates translation of the JUN mRNA which encodes the transcription factor JUN, an oncogenic transcription factor involved in cell cycle progression, apoptosis, and cell proliferat...

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Detalles Bibliográficos
Autores principales: González-Sánchez, Angélica M., Castellanos-Silva, Eimy A., Díaz-Figueroa, Gabriela, Cate, Jamie H. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680820/
https://www.ncbi.nlm.nih.gov/pubmed/38014201
http://dx.doi.org/10.1101/2023.11.17.567602