Reversible histone deacetylase activity catalyzes lysine acylation

Starvation and low carbohydrate diets lead to the accumulation of the ketone body, β-hydroxybutyrate (BHB), whose blood concentrations increase more than 10-fold into the millimolar range. In addition to providing a carbon source, BHB accumulation triggers lysine β-hydroxybutyrylation (Kbhb) of prot...

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Detalles Bibliográficos
Autores principales: Tsusaka, Takeshi, Najar, Mohd. Altaf, Schwarz, Benjamin, Bohrnsen, Eric, Oses-Prieto, Juan A., Lee, Christina, Burlingame, Alma L., Bosio, Catharine M., Burslem, George M., Goldberg, Emily L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680841/
https://www.ncbi.nlm.nih.gov/pubmed/38014285
http://dx.doi.org/10.1101/2023.11.17.567549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680841/
https://www.ncbi.nlm.nih.gov/pubmed/38014285
http://dx.doi.org/10.1101/2023.11.17.567549

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