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Differential responses of primary neuron-secreted MCP-1 and IL-9 to type 2 diabetes and Alzheimer’s disease-associated metabolites

Type 2 diabetes (T2D) is implicated as a risk factor for Alzheimer’s disease (AD), the most common form of dementia. In this work, we investigated neuroinflammatory responses of primary neurons to potentially circulating, blood-brain barrier (BBB) permeable metabolites associated with AD, T2D, or bo...

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Detalles Bibliográficos
Autores principales: Ball, Brendan K., Kuhn, Madison K., Fleeman, Rebecca M., Proctor, Elizabeth A., Brubaker, Douglas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680853/
https://www.ncbi.nlm.nih.gov/pubmed/38014333
http://dx.doi.org/10.1101/2023.11.17.567595