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Alcohol and e-cigarette damage alveolar-epithelial barrier by activation of P2X7r and provoke brain endothelial injury via extracellular vesicles

BACKGROUND: Use of nicotine containing products like electronic cigarettes (e-Cig) and alcohol are associated with mitochondrial membrane depolarization, resulting in the extracellular release of ATP, and mitochondrial DNA (mtDNA), mediating inflammatory responses. While nicotine effects on lungs is...

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Detalles Bibliográficos
Autores principales: Mekala, Naveen, Trivedi, Jayshil, Bhoj, Priyanka, Togre, Namdev, Rom, Slava, Sriram, Uma, Persidsky, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680944/
https://www.ncbi.nlm.nih.gov/pubmed/38014253
http://dx.doi.org/10.21203/rs.3.rs-3552555/v1