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Mutation divergence over space in tumour expansion

Mutation accumulation in tumour evolution is one major cause of intra-tumour heterogeneity (ITH), which often leads to drug resistance during treatment. Previous studies with multi-region sequencing have shown that mutation divergence among samples within the patient is common, and the importance of...

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Detalles Bibliográficos
Autores principales: Li, Haiyang, Yang, Zixuan, Tu, Fengyu, Deng, Lijuan, Han, Yuqing, Fu, Xing, Wang, Long, Gu, Di, Werner, Benjamin, Huang, Weini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681009/
https://www.ncbi.nlm.nih.gov/pubmed/37989227
http://dx.doi.org/10.1098/rsif.2023.0542