Nrf1 is not a direct target gene of SREBP1, albeit both are integrated into the rapamycin-responsive regulatory network in human hepatoma cells

The essential role of protein degradation by ubiquitin-proteasome system is exerted primarily for maintaining cellular protein homeostasis. The transcriptional activation of proteasomal genes by mTORC1 signaling depends on Nrf1, but whether this process is directly via SREBP1 remains elusive. In thi...

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Detalles Bibliográficos
Autores principales: Liu, Keli, Hu, Shaofan, Qiu, Lu, Wang, Meng, Zhang, Zhengwen, Sun, Guiyin, Zhang, Yiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681226/
https://www.ncbi.nlm.nih.gov/pubmed/38011090
http://dx.doi.org/10.1371/journal.pone.0294508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681226/
https://www.ncbi.nlm.nih.gov/pubmed/38011090
http://dx.doi.org/10.1371/journal.pone.0294508

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