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Human umbilical cord-derived mesenchymal stem cells alleviate oxidative stress-induced islet impairment via the Nrf2/HO-1 axis

Hyperglycaemia-induced oxidative stress may disrupt insulin secretion and β-cell survival in diabetes mellitus by overproducing reactive oxygen species. Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) exhibit antioxidant properties. However, the mechanisms by which hUC-MSCs protect β-...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Cao, Baige, Zhou, Yang, Zhang, Huina, Wang, Congrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681279/
https://www.ncbi.nlm.nih.gov/pubmed/37245063
http://dx.doi.org/10.1093/jmcb/mjad035