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A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile

A genomic signature for endosporulation includes a gene coding for a protease, YabG, which in the model organism Bacillus subtilis is involved in assembly of the spore coat. We show that in the human pathogen Clostridioidesm difficile, YabG is critical for the assembly of the coat and exosporium lay...

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Detalles Bibliográficos
Autores principales: Marini, Eleonora, Olivença, Carmen, Ramalhete, Sara, Aguirre, Andrea Martinez, Ingle, Patrick, Melo, Manuel N., Antunes, Wilson, Minton, Nigel P., Hernandez, Guillem, Cordeiro, Tiago N., Sorg, Joseph A., Serrano, Mónica, Henriques, Adriano O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681294/
https://www.ncbi.nlm.nih.gov/pubmed/37956166
http://dx.doi.org/10.1371/journal.ppat.1011741