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Checkpoint phosphorylation sites on budding yeast Rif1 protect nascent DNA from degradation by Sgs1-Dna2
In budding yeast the Rif1 protein is important for protecting nascent DNA at blocked replication forks, but the mechanism has been unclear. Here we show that budding yeast Rif1 must interact with Protein Phosphatase 1 to protect nascent DNA. In the absence of Rif1, removal of either Dna2 or Sgs1 pre...
Autores principales: | Gali, Vamsi Krishna, Monerawela, Chandre, Laksir, Yassine, Hiraga, Shin-ichiro, Donaldson, Anne D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681312/ https://www.ncbi.nlm.nih.gov/pubmed/37956214 http://dx.doi.org/10.1371/journal.pgen.1011044 |
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