Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway

Dosage optimization to maximize efficacy and minimize toxicity is a potential issue when administering radiotherapy (RT) in combination with immune checkpoint blockade (ICB) or inhibitors of the DNA Damage Response Pathway (DDRi) in the clinic. Preclinical models and mathematical modeling can help i...

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Detalles Bibliográficos
Autores principales: Hodson, David, Mistry, Hitesh, Guzzetti, Sofia, Davies, Michael, Staniszewska, Anna, Farrington, Paul, Cadogan, Elaine, Yates, James, Aarons, Leon, Ogungbenro, Kayode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681475/
https://www.ncbi.nlm.nih.gov/pubmed/37722071
http://dx.doi.org/10.1002/psp4.13026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681475/
https://www.ncbi.nlm.nih.gov/pubmed/37722071
http://dx.doi.org/10.1002/psp4.13026

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