Building an adaptive dose simulation framework to aid dose and schedule selection

Establishing a dosing regimen that maximizes clinical benefit and minimizes adverse effects for novel therapeutics is a key objective for drug developers. Finding an optimal dose and schedule can be particularly challenging for compounds with a narrow therapeutic window such as in oncology. Modeling...

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Detalles Bibliográficos
Autores principales: Hooijmaijers, Richard, Parasrampuria, Ridhi, Marostica, Eleonora, Ferron‐Brady, Geraldine, Post, Teun M., Visser, Sandra A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Tutorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681481/
https://www.ncbi.nlm.nih.gov/pubmed/37574587
http://dx.doi.org/10.1002/psp4.13027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681481/
https://www.ncbi.nlm.nih.gov/pubmed/37574587
http://dx.doi.org/10.1002/psp4.13027

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