Superanionic DNA: enzymatic synthesis of hypermodified DNA bearing four different anionic substituents at all four nucleobases

We designed and synthesized a set of four 2′-deoxyribonucleoside 5′-O-triphosphates (dNTPs) derived from 5-substituted pyrimidines and 7-substituted 7-deazapurines bearing anionic substituents (carboxylate, sulfonate, phosphonate, and phosphate). The anion-linked dNTPs were used for enzymatic synthe...

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Detalles Bibliográficos
Autores principales: Kuprikova, Natalia, Ondruš, Marek, Bednárová, Lucie, Riopedre-Fernandez, Miguel, Slavětínská, Lenka Poštová, Sýkorová, Veronika, Hocek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681718/
https://www.ncbi.nlm.nih.gov/pubmed/37870471
http://dx.doi.org/10.1093/nar/gkad893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681718/
https://www.ncbi.nlm.nih.gov/pubmed/37870471
http://dx.doi.org/10.1093/nar/gkad893

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