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Superanionic DNA: enzymatic synthesis of hypermodified DNA bearing four different anionic substituents at all four nucleobases
We designed and synthesized a set of four 2′-deoxyribonucleoside 5′-O-triphosphates (dNTPs) derived from 5-substituted pyrimidines and 7-substituted 7-deazapurines bearing anionic substituents (carboxylate, sulfonate, phosphonate, and phosphate). The anion-linked dNTPs were used for enzymatic synthe...
Autores principales: | Kuprikova, Natalia, Ondruš, Marek, Bednárová, Lucie, Riopedre-Fernandez, Miguel, Slavětínská, Lenka Poštová, Sýkorová, Veronika, Hocek, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681718/ https://www.ncbi.nlm.nih.gov/pubmed/37870471 http://dx.doi.org/10.1093/nar/gkad893 |
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