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An archaeal virus-encoded anti-CRISPR protein inhibits type III-B immunity by inhibiting Cas RNP complex turnover

CRISPR–Cas systems are widespread in prokaryotes and provide adaptive immune against viral infection. Viruses encode a type of proteins called anti-CRISPR to evade the immunity. Here, we identify an archaeal virus-encoded anti-CRISPR protein, AcrIIIB2, that inhibits Type III-B immunity. We find that...

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Detalles Bibliográficos
Autores principales: Liu, Jilin, Li, Qian, Wang, Xiaojie, Liu, Zhenzhen, Ye, Qing, Liu, Tao, Pan, Saifu, Peng, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681719/
https://www.ncbi.nlm.nih.gov/pubmed/37850639
http://dx.doi.org/10.1093/nar/gkad804