BOLA3 and NFU1 link mitoribosome iron–sulfur cluster assembly to multiple mitochondrial dysfunctions syndrome

The human mitochondrial ribosome contains three [2Fe–2S] clusters whose assembly pathway, role, and implications for mitochondrial and metabolic diseases are unknown. Here, structure-function correlation studies show that the clusters play a structural role during mitoribosome assembly. To uncover t...

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Detalles Bibliográficos
Autores principales: Zhong, Hui, Janer, Alexandre, Khalimonchuk, Oleh, Antonicka, Hana, Shoubridge, Eric A, Barrientos, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681725/
https://www.ncbi.nlm.nih.gov/pubmed/37823603
http://dx.doi.org/10.1093/nar/gkad842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681725/
https://www.ncbi.nlm.nih.gov/pubmed/37823603
http://dx.doi.org/10.1093/nar/gkad842

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