Circadian Clock REV-ERBs Agonist SR9009 Induces Synergistic Antitumor Activity in Multiple Myeloma by Suppressing Glucose-Regulated Protein 78-Dependent Autophagy and Lipogenesis

BACKGROUND: Proteasome inhibitors, such as bortezomib, have demonstrated efficacy in the therapeutic management of multiple myeloma (MM). However, it is important to note that these inhibitors also elicit endoplasmic reticulum stress, which subsequently triggers the unfolded protein response (UPR) a...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Liu, Shu Ling, Guo, Quan Quan, Shi, Xiao Hong, Ma, Mei Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681778/
https://www.ncbi.nlm.nih.gov/pubmed/38022411
http://dx.doi.org/10.14740/wjon1681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681778/
https://www.ncbi.nlm.nih.gov/pubmed/38022411
http://dx.doi.org/10.14740/wjon1681

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