mtFociCounter for automated single-cell mitochondrial nucleoid quantification and reproducible foci analysis

Mitochondrial DNA (mtDNA) encodes the core subunits for OXPHOS, essential in near-all eukaryotes. Packed into distinct foci (nucleoids) inside mitochondria, the number of mtDNA copies differs between cell-types and is affected in several human diseases. Currently, common protocols estimate per-cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Rey, Timo, Tábara, Luis Carlos, Prudent, Julien, Minczuk, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681798/
https://www.ncbi.nlm.nih.gov/pubmed/37850644
http://dx.doi.org/10.1093/nar/gkad864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681798/
https://www.ncbi.nlm.nih.gov/pubmed/37850644
http://dx.doi.org/10.1093/nar/gkad864

Ejemplares similares